Valproate and 4-methyloctanoic acid, an analogue of valproate, in animal models of epilepsy

Valproic acid (VPA) is a commonly used drug for the treatment of epilepsy, bipolar disorder and migraine, yet its mechanisms of action are unknown. The neuroprotective effect of VPA has been hypothesized to be secondary to inhibition of the cAMP/protein kinase A (PKA) pathway. Here, the result show...

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Bibliographic Details
Main Author: Chang, P.-S.
Published: University College London (University of London) 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564832