Human genetic variation with implications for healthcare in Ethiopian populations

Cytochrome P450 1A2 metabolizes a wide range of therapeutic drugs, including several used to treat diseases common in sub-Saharan Africa. Variation in the gene (CYP1A2) has been reported to be associated with differential efficacy of therapeutic drugs and adverse drug reactions. To gain a better und...

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Bibliographic Details
Main Author: Browning, S. L.
Published: University College London (University of London) 2010
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564829