Protocol development for analysis of the DMPK repeat in preimplantation genetic diagnosis and the investigation of gene expression in human oocytes and blastocysts
Myotonic dystrophy type 1 (DM1) is an autosomal dominant disorder caused by expansion of an unstable CTG repeat within the 3’UTR of the DMPK gene, which expands further in length during transmission from generation to generation. Prenatal diagnosis is available, although the decision for pregnancy t...
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University College London (University of London)
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564726 |