Study of the cell biological role of Lowe Syndrome protein OCRL1
Oculocerebrorenal syndrome of Lowe (OCRL) is caused by mutations in a phosphatidylinositol 5-phosphatase, OCRL1, and is believed to lead to an elevation of its preferred substrate, PI(4,5)P2. To date, much of the work on OCRL1 has centred on its role at Golgi and endosomal membranes. However, there...
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University College London (University of London)
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564700 |