Complement Factor H : solution structures and interactions with ligands

Factor H (FH) is a plasma glycoprotein that plays a central role in regulating the alternative pathway of complement. It is composed of 20 short complement regulator (SCR) domains. The SCR-1/5 fragment is required for decay acceleration and cofactor activity, while the SCR-16/20 fragment possesses b...

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Bibliographic Details
Main Author: Okemefuna, A. I.
Published: University College London (University of London) 2009
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.564681