The importance of domain-domain interactions in the regulation and activity of neuronal nitric oxide synthase
Nitric oxide synthases (NOSs) catalyse the production of the physiological messenger molecule NO from L-arginine in a unique two step oxygenation reaction. Constitutive forms of NOS are activated by the binding of calmodulin (CaM) to a 20- amino-acid inter-domain region in the presence of calcium io...
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University of Edinburgh
2008
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.562255 |