Next-generation sequencing analysis of DNA methylation in acute myeloid leukaemia

DNA methylation has an emerging role in pathogenesis and diagnosis of acute myeloid leukaemia (AML). In order to obtain a global view of the DNA methylation changes in AML genome, we applied methylated DNA immunoprecipitation followed by next-generation sequencing (MeDIP-seq) to AML patients from 4...

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Bibliographic Details
Main Author: Saied, Marwa Hanafi Mahmoud
Published: Queen Mary, University of London 2012
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.561235