Mutational and computational characterization of transmembrane domains in the fungal G protein-coupled pheromone receptors STE2 and Mam2

G protein-coupled receptors (GPCRs) comprise the largest family of cell-surface receptors involved in sensing a multitude of ligands and are consequently attractive pharmacological targets. Their study is complicated by cross-talk between signalling pathways and altered receptor pharmacology due to,...

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Bibliographic Details
Main Author: Nilsson Lock, Gun Antonia Evelina
Published: University of Warwick 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.560259