Investigation of the expression pattern and functional importance of the Gnasxl-encoded XLαs protein of the imprinted Gnas Locus
XLαs is a NH2-terminal splice variant of the stimulatory G-protein α-subunit Gsα. Both are encoded by the imprinted Gnas locus. Similar to Gsα, XLαs can couple 7-TM receptors to adenylate cyclase in cultured cells. Previously, a knock-out mouse specific for the Gnasxl transcript was generated (Gnasx...
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University of Liverpool
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.559431 |