Investigation of ligand-induced conformational changes of the dopamine D2s receptor using fluorescence resonance energy transfer

Approximately 50 % of current pharmaceutical drugs target the G protein-coupled receptor (GPCR) family, rendering an understanding of the mechanisms behind their actions critical. Dopamine is a key neurotransmitter involved in motor function and behaviour and has been associated with disorders such...

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Bibliographic Details
Main Author: Fotheringham, Helen L.
Published: University of Reading 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558734