Using human genomic constructs of Preselenin-1 gene to understand its pathological role in Alzheimer's disease
Alzheimer's disease (AD) is the most common neurodegenerative disorder in the developed world. While the more common late-onset AD (LOAD) is associated with genetic and environmental risk factors, the early-onset (EOAD) form is most commonly caused by mutations in the Presenilin 1 (PSi) gene. S...
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University of Oxford
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.558687 |