Fluoxetine prevents the cognitive and cellular effects of chemotherapy in the adult hippocampus

Rationale: CMF (cyclophosphamide: CP; methotrexate: MTX; 5-fluorouracil: 5-FU) is a chemotherapy combination associated with the cognitive impairments which many cancer patients experience after treatment. A reduction in hippocampal neurogenesis is a known means by which cytotoxic drugs alter cognit...

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Bibliographic Details
Main Author: Lyons, Laura
Published: University of Nottingham 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555733