A novel 1,3-dipolar cycloaddition strategy towards securinine and virosecurinine
This thesis describes the development of a novel synthetic route towards the Securinega alkaloids, securinine 1 and virosecurinine 2. The key reaction in this innovative approach is the l,3-dipolar cycloaddition between pyridinium stabilised ylides 169 and γ,δ-unsaturated butenolides 142, to form sp...
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University of Nottingham
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555691 |