Modelling reaction mechanisms and dynamics of cytochrome P450-drug complexes
The ability to predict the reactivity and selectivity of cytochrome P450 en- zymes using computational methods has the potential to reduce the number of late- stage failures in the drug discovery process. The antiinfiammatory drug diclofenac and anticancer therapy tamoxifen provide interesting test-...
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University of Bristol
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.555631 |