A radical cascade approach to the skeleton of α−Cyclopiazonic Acid
3-Nitrophthalic acid 2.04 was transformed into 2.10 in 38% yield. Vinylglycine derivative was synthesised from D-Methionine 2.12 in 42% yield. (For image see abstract in pdf) Compounds 2.10 and 2.16 were coupled using Grubbs' 2nd generation catalyst creating 2.25. Unfortunately attempts to oxid...
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University of Sussex
2012
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554774 |