Transcriptional and post-transcriptional control of DNMT1 in oocytes and somatic cells
In mammals, the DNA methylation patterns are established by the de novo methyltransferases of the DNMT3 family and subsequently maintained DNMTl. The DNA methylation patterns of imprinted genes are established during gametogenesis. Many imprinted genes are found methylated on the maternal allele, an...
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University of Ulster
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554332 |