On the effects of large-scale transcriptomics datasets on gene functional analyses

The Guilt-by-Association (GBA) principle, according to which genes with similar expression profiles are functionally associated, is widely applied for functional analyses using large heterogeneous collections of transcriptomics data. In this thesis we show that using such large collections could ham...

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Bibliographic Details
Main Author: Bhat, Prajwal
Published: Royal Holloway, University of London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553731