Investigating the effects or AKT/PKB inhibitors on [18F]-FDG uptake in cancer cells
Increased AKT activity due to hyperactivated PI3K or inactivation of PTEN is frequently found in cancer. Thus the development of AKT inhibitors and pharmacodynamic (PO) biomarkers for AKT inhibition is of major interest for cancer therapy. [18F]-FDG PET is a non-invasive imaging technique which allo...
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Institute of Cancer Research (University Of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553702 |