Cis-selectivity in the Pictet-Spengler reaction and studies towards the synthesis of indole alkaloids

Previous work in our group as been directed towards the synthesis of (+)-ajmaline, a biologically important indole alkaloid. Its total synthesis was completed in the 1990s. An important early step in its total synthesis from D-tryptophan is the trans-selective Pictet-Spengler reaction. However, in o...

Full description

Bibliographic Details
Main Author: Beard, Mark
Other Authors: Bailey, Pat; Thomas, Jim
Published: University of Manchester 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553317