Characterisation of TRAIL receptor signalling to apoptosis in pre-clinical models of breast cancer
TNF-Related Apoptosis-Inducing Ligand (TRAIL) belongs to the TNF cytokine family and can signal to apoptosis by binding to either of two membrane-bound death receptors, TRAIL-R1 or TRAIL-R2. Using ligands specific for TRAIL-R1 (R1L) or TRAIL-R2 (R2L), our laboratory has previously shown that combini...
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University of Leicester
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551860 |