Functional analysis of regulatory phosphorylation events in cardiac KATP channel subunits in ischaemia

Protein kinase C (PKC)–mediated phosphorylation of ATP sensitive potassium channels (KATP) is believed to be involved in ischaemic preconditioning. Five consensus PKC phosphorylation sites in the Kir6.1 subunit, S354, S379, S385, S391 and S397, have been proposed as possible regulatory sites. The ob...

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Bibliographic Details
Main Author: Siriwittayawan, Duangduan
Other Authors: Norman, Robert
Published: University of Leicester 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551835