DNA hypomethylation in radiosensitivity and genomic stability
Exposure to ionising radiation can result in genome destabilisation. Genomic instability is observed in many cancers and is thought to lead to tumourigenesis. A correlation between genomic instability and global hypomethylation, another common feature of tumour cells, has been demonstrated and attri...
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University of Leicester
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551769 |