Investigation of the mechanism that underlies MS32 minisatellite instability in cells that use the alternative lengthening of telomeres pathway
Cancer cells escape senescence by activating a telomere maintenance mechanism (TMM) to elongate telomeres and continue dividing. The most common TMM is the enzyme telomerase that adds telomeric repeats. However, some cancer cells activate the Alternative Lengthening of Telomeres (ALT), a recombinati...
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University of Leicester
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551746 |