Quadruplex folding within double helical segments of gene regulatory regions

Gene regulatory regions, such as promoters or introns in the human genome, are rich in putative quadruplex forming sequences. G-quadruplex formation in these duplex regions requires the opening of duplex so that the single stranded region can fold into a G-quadruplex. The factors that affect the tra...

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Bibliographic Details
Main Author: Lam, Wan Chi
Published: University of Ulster 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.551557