Natural killer cell recognition and killing of virally-transformed and cancer cells

Natural Killer (NK) cells are important in the elimination of virally-infected and cancer cells. NK cell recognise changes in surface molecules on cells, which can cause an NK cell to kill the target cell by either ligation of death receptors or perforin-mediated release of granzymes. Granzymes are...

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Bibliographic Details
Main Author: Bowles, Paul Anthony
Published: University of Leeds 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550269