Balancing potency and differentiation in mouse embryo-derived stem cells and in vivo

An inherent challenge for developing organisms is to maintain a critical balance between cell potency and differentiation. This is most obvious in embryonic stem (ES) cells where genetic, epigenetic and cell signalling pathways support ES cell ability to self-renew and to generate all embryonic line...

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Bibliographic Details
Main Author: Helness, Anne Christine
Other Authors: Azuara, Veronique
Published: Imperial College London 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.549776