Role of heparan sulphate in inflammation and allograft rejection

Transplantation is often the only therapy for end-stage organ failure. Blood-borne leukocytes are guided into the grafts by proinflammatory chemokines. To achieve full functionality, chemokines interact with heparan sulphate (HS) proteoglycans, which are expressed on the majority of all animal cell...

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Bibliographic Details
Main Author: Spielhofer, Julia
Published: University of Newcastle upon Tyne 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.548020