Identification and characterisation of the linear ubiquitin chain assembly complex (LUBAC) as a functionally important component of the CD40 receptor signalling complex
CD40 is a member of the Tumour Necrosis Factor (TNF)-Receptor superfamily and plays an important role in maturation and differentiation of dendritic cells and B cells. In B cells, CD40 provides a costimulatory signal and facilitates differentiation, germinal centre formation and isotype switching. S...
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Imperial College London
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.543332 |