An investigation into the interacting partners of the ubiquitin ligase, SIAH1, and the tumour suppressor protein, ASPP1
Selective protein degradation is a crucial control mechanism which impacts nearly every aspect of eukaryotic cell biology. It is achieved via the ubiquitin-proteasome pathway whereby multimers of ubiquitin are conjugated to substrate proteins and subsequently recognised and degraded by the proteasom...
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University of Newcastle Upon Tyne
2011
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542214 |