Investigating the role of Bmi-1 in liver growth and function

Bmi-1 is a member of the Polycomb group (PcG) family of transcriptional repressors, which are implicated in the maintenance of embryonic and adult stem cells. Previous reports indicate that Bmi-1 plays a key role in repressing the Ink4a/Arf tumour suppressor locus. Overexpression of Bmi-1 in putativ...

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Bibliographic Details
Main Author: Elder, Alex Kenneth
Published: Queen Mary, University of London 2011
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542041