Diastereoselective synthesis of 2,4,5 trisubstituted piperidines : application in natural product synthesis

This thesis describes the diastereoselective synthesis of 2,4,5-trisubstituted piperidines using carbonyl-ene and Prins cyclisations and their application in natural product synthesis. Following on from previous work in the group, we investigated how a preinstalled substituent in the 2-position can...

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Bibliographic Details
Main Author: Sadler, Matthew James
Published: University of Birmingham 2011
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.541251