Investigation of the cAMP pathway in axon growth and guidance
Our investigation suggests that Epac, and not the canonical PKA, is the main effector involved in cAMP-mediated axon growth and guidance, and that the MAPK regulator, B-Raf, can be differentially regulated by both Epac and PKA. Direct activation of Epac induces activation of B-Raf, whereas activati...
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University of Aberdeen
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.540466 |