Gene expression profiling and proteomic analysis of cartilage degradation in a mouse model of osteoarthritis

Osteoarthritis (OA) is characterised by articular cartilage degradation and changes in associated joint tissues. It is a common condition, which causes significant pain and disability. Aetiological factors include age, mechanical stress, genetic predisposition and obesity. The exact sequence of mole...

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Bibliographic Details
Main Author: Gardiner, Matthew David
Other Authors: Nagase, Hideaki ; Nanchahal, Jagdeep
Published: Imperial College London 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.539255