Dock180/Elmo proteins are critical regulators of phagocytosis, macropinocytosis and chemotaxis in Dictyostelium

In this study, we report the characterization of Dock/Elmo proteins, a novel family of RacGEF's in Dictyostelium discoideum and describe their role in phagocytosis, macropinocytosis and CAMP mediated chemotactic cell movement. Aggregation competent Dictyostelium cells can detect and move up cAM...

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Bibliographic Details
Main Author: Wang, Jun
Other Authors: Weijer, Cornelis
Published: University of Dundee 2006
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.537915