WNK1 and its role in hypertension

WNK1 is a serine-threonine protein kinase involved in blood pressure (BP) control and electrolyte homeostasis. Intronic deletions in the WNK1 gene result in over-expression and lead to pseudohypoaldosteronism type II, a disorder characterized by hypertension and hyperkalemia. We have previously repo...

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Bibliographic Details
Main Author: Hoti, Mimoza
Published: Queen Mary, University of London 2010
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535842