In vivo assessment of non-dopaminergic systems in Parkinson's disease with Positron Emission Tomography

Parkinson's disease (PD) is characterized by a progressive loss of nigrostriatal dopaminergic neurons. Non-dopaminergic neurotransmission is also impaired. Intraneuronal Lewy bodies, the pathological hallmark of PD, have been observed in serotoninergic, noradrenergic, and cholinergic neurons. D...

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Bibliographic Details
Main Author: Pavese, Nicola
Other Authors: Brooks, David
Published: Imperial College London 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.535608