Exploring the role of inflammatory mediators in the 1-methyl-4-phenly-1,2,3,6,-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

The roles of the potential immune regulators, peroxisome proliferator-activated receptors (PPARs) and the major histocompatibility complex class II (MHC II), were explored in the MPTP model of PD. Both PPARδ and PPARγ were expressed in the dopaminergic neurons affected in PD. PPARδ was also expresse...

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Bibliographic Details
Main Author: Martin, Heather Louise
Published: University of Aberdeen 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.531882