The role of protein aggregation in Huntington's disease
Huntington’s disease (HD) is a hereditary progressive neurodegenerative disorder characterised by chorea, general motor impairment, psychiatric disturbances and dementia, leading to death within 10 to 20 years of onset. It is caused by a (CAG)n trinucleotide repeat expansion in the gene IT15 that is...
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University of Leicester
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530566 |