Cellular and molecular characterisation of familial haemophagocytic lymphohistiocytosis type 1

Haemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition in which absent or markedly reduced T cell and natural killer (NK) cell cytotoxicity results in uncontrolled proliferation of T cells, activation of macrophages, hypercytokinaemia, pancytopaenia, and hepatosplenomegaly...

Full description

Bibliographic Details
Main Author: Chakravorty, Subarna
Other Authors: Layton, Mark ; Karadimitris, Anastasios
Published: Imperial College London 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.530262