Host cell factors in ovarian cancer influencing efficacy of oncolytic aenovirus dl922-947
Adenoviral gene therapy holds great potential for cancer treatment, but is limited by a lack of efficient vectors. dl922-947, an E1A CR2-deleted adenovirus, replicates selectively within and lyses cancer cells. It is believed that its selectivity depends upon abnormalities in the cell cycle regulato...
| Main Author: | |
|---|---|
| Published: |
Queen Mary, University of London
2010
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.528406 |