Transplantation tolerance through the modulation of dendritic cells
Allogeneic T cell stimulation requires antigen recognition through the T cell receptor and costimulatory signals provided by antigen presenting cells (APCs). For naïve T cells stimulation, interaction between CD28 on T cells and CD80/86 on dendritic cells (DCs) provides an essential costimulatory si...
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Imperial College London
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.527768 |