Investigation of the role of novel SGK1 isoforms in regulation of sodium transport in kidney epithelial cells
Serum/glucocorticoid regulated kinase 1 (SGK1) is a key component of the pathway that leads to activation of the epithelial sodium channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN). Regulation of ENaC is a major determinant of renal Na+ absorption and overall body fluid homeostasis a...
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University of Newcastle Upon Tyne
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.525032 |