Analysis of Bcl6 in a genetically tractable human B cell line

B cell lymphoma 6 (Bcl6) is a proto-oncogene functioning as a transcriptional repressor at the germinal centre (GC) stage of B cell development, regulating proliferation, differentiation and survival. Bcl6 is commonly dysregulated in GCderived lymphomas and hence a promising therapeutic target. Alth...

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Bibliographic Details
Main Author: Zobel, Jennifer
Other Authors: Porter, Andy ; Wagner, Simon
Published: Imperial College London 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.522209