Cancer risk and biomarker analysis in mismatch repair deficient colorectal carcinoma
Lynch Syndrome is caused by mutations in the DNA mismatch repair (MMR) genes; MLH1, MSH2, MSH6 and PMS2. An accurate estimation of cancer risk for MMR mutation carriers is essential for counselling and screening. United Kingdom (UK) specific cancer risks for MMR mutation carriers and cumulative colo...
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University of Manchester
2009
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516737 |