Cancer risk and biomarker analysis in mismatch repair deficient colorectal carcinoma

Lynch Syndrome is caused by mutations in the DNA mismatch repair (MMR) genes; MLH1, MSH2, MSH6 and PMS2. An accurate estimation of cancer risk for MMR mutation carriers is essential for counselling and screening. United Kingdom (UK) specific cancer risks for MMR mutation carriers and cumulative colo...

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Bibliographic Details
Main Author: Barrow, Emma
Published: University of Manchester 2009
Subjects:
611
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516737