Assessment and development of adenovirus type 11 for cancer therapy
The efficacy of oncolytic virotherapy is influenced by the interactions between the tumour, virus and host immunity. The first generation of oncolytic adenoviruses, based on serotype 5 (Ad5), has achieved limited success in clinical trials. Its shortcomings include the downregulation and inaccessibi...
| Main Author: | |
|---|---|
| Published: |
Queen Mary, University of London
2010
|
| Subjects: | |
| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516700 |