Increased senescence and altered ECM remodelling in oral submucous fibrosis
Background: Oral submucous fibrosis (OSMF) is a pre-neoplastic condition, causally linked to areca nut consumption, the pathogenesis of which is poorly understood. TGF-β and disturbances in the balance between MMPs and TIMPs have been implicated in increased collagen deposition and fibrosis but no p...
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Queen Mary, University of London
2010
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516699 |