AFM investigations of critical interactions in the Bacillus primosome and Cryogenic AFM : a new tool for structural biology

In this thesis for the first AFM has been employed for the high resolution imaging of a protein assembly. The DnaB-DnaG Helicase-Primase interaction in Bacillus is the key reaction that causes the switch from primase mode to polymerisation mode. This assembly was imaged using the AFM to a sub-molecu...

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Bibliographic Details
Main Author: Turner, Ian James
Published: University of Nottingham 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.514630