Engineering glycan-binding proteins for the detection, analysis and treatment of cancer cells

Aberrant glycosylation in cancer cells can often lead to an increase in the exposure of unusual glycan structures. The presence of these structures can be exploited by engineering glycan-binding proteins as novel tools for the characterisation of glycoproteins bearing cancer-associated glycan struct...

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Bibliographic Details
Main Author: Powlesland, Alex Stephen
Other Authors: Taylor, Maureen ; Drickamer, Kurt
Published: Imperial College London 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513502