Endoplasmic reticulum stress and inhibition of apoptotic caspases regulate the life-span of short-lived plasma cells

Plasma cells are the terminally differentiated effector cells of the humoral immune system. The majority of plasma cells are short-lived and undergo programmed cell death in the form of apoptosis after few days of intensive immunoglobulin secretion. Despite potentially wide-ranging implications for...

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Bibliographic Details
Main Author: Auner, Holger Werner
Other Authors: Dillon, Niall ; Sabbattini, Pierangela
Published: Imperial College London 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513457