Applications of the achmatowicz rearrangement in natural product synthesis

The structurally related PM-94128 and Ajudazols A and B exhibit differing biological activities but share the isocoumarin core structure. PM-94128 belongs to a large family of compounds known as the aminodihydroisocoumarins and was isolated in 1997. It has been shown to be an inhibitor of DNA and RN...

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Bibliographic Details
Main Author: Hobson, Stephen
Published: University of Glasgow 2010
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513227